Cytoplasmic transfer of heritable elements other than mtDNA from SAMP1 mice into mouse tumor cells suppresses their ability to form tumors in C57BL6 mice

Aqueous Extract of Nigella sativa Seeds Suppresses Testicular Steroidogenesis In Mice Leydig Cells, in vitro

Nigella sativa (black seed) is an important medicinal herb with folkloric use in wide range of diseases. It is well studied for its biological activities. However, there is limited information regarding its effect on the male reproductive system. This study describes the effect of the aqueous extract of N. sativa (NSE) on testicular steroidogenesis from mice Leydig cells in vitro . Mice tes...

The ability of mouse nuclear transfer embryonic stem cells to differentiate into primordial germ cells

Nuclear transfer embryonic stem cells (ntESCs) show stem cell characteristics such as pluripotency but cause no immunological disorders. Although ntESCs are able to differentiate into somatic cells, the ability of ntESCs to differentiate into primordial germ cells (PGCs) has not been examined. In this work, we examined the capacity of mouse ntESCs to differentiate into PGCs in vitro. ntESCs agg...

Swim training suppresses tumor growth in mice.

The present study was designed to determine the effects of physical training on the development of cancer induced by the injection of Ehrlich tumor cells in mice. Male Swiss mice were subjected to a swim training protocol (5 days/wk for 6 wk, 1 h at 50% of maximal capacity-trained groups) or remained sedentary in their cages (sedentary groups). The inoculation of Ehrlich tumor cells was perform...

Comparison of Neonatal and Adult Mice-derived Sertoli Cells in Support of Expansion of Mouse Spermatogonial Stem Cells In vitro

Adoptive transfer of immunity to intraocular tumors in mice.

Allogeneic tumors, transplanted into the anterior chamber of the mouse eye, grow progressively and eventually kill the host. However, recipients that have been previously immunized to the alloantigens of the tumor are completely resistant to intracameral tumor challenge. In the present study the authors examined the role of specific immune effector elements in preventing, controlling, or eradic...